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Dipl.-Troph.
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Phone office: +49-(0)551-39 6711
Phone lab: +49-(0)551-39 22749
Email: antje.schubert@med.uni-goettingen.de
Project:
Development of cytotoxic conjugates of the proprietary cytotoxic compound disorazol
Z and peptides targeting G-protein coupled receptors, including LHRH receptors. (BMBF
Funding)
Funding:
- Deutsche Krebshilfe (Thesis: Effects of GnRH analogs on migration and
invasion of breast cancer cells)
- BMBF / Aeterna-Zentaris Inc. 01.02.2011 - 31.01.2014
Publications:
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Schubert A, Schulz H, Emons G, Gründker
C (2008) Expression of OPG and RANKL in HCC70 breast cancer cells and effects of
GnRH treatment on RANKL expression. Gynecological Endocrinology 24(6):331-338
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Olbrich T, Ziegler E, Türk G, Schubert
A, Emons G, Gründker C (2010) Kisspeptin-10 inhibits bone-directed migration
of GPR54-positive breast cancer cells: evidence for a dose-window effect. Gynecologic
Oncology 119:571-578
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Schubert A, Hawighorst T, Emons G, Gründker
C (2011) Agonist and antagonists of GnRH-I and -II reduce metastasis of triple-negative
human breast cancer cells in vivo. Breast Cancer Research and Treatment
130(3): 783-790
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